Main board tp ms338 pb801. the most important fact in a situation: 3. chief or principal in rank, importance, size, etc 2. the chief or principal part or point: The main of their investments was lost during the war. sheer or utmost (esp in the phrase by main force) the principal or most important part or point usually in the phrase in the main, mostly, chiefly The main thing is to keep calm and don’t get angry. Guest Feedback. Learn more. physical strength, power, or force: to struggle with might and main. main (meɪn) adj (prenominal) 1. Main definition: Most important; principal. Find the latest Main Street Capital Corporation (MAIN) stock quote, history, news and other vital information to help you with your stock trading and investing. Check Gift Card Balance. . Get in Touch. How to use main in a sentence. a pipe that carries…. Contact. The main social event of the summer was a dance and reception. Careers. PURCHASE eGIFT CARD. The meaning of MAIN is physical strength : force —used in the phrase with might and main. Main refers to the primary or most important aspect or part of something. It signifies the central or principal focus, significance, or purpose of a subject or object. The meaning of MAIN is physical strength : force —used in the phrase with might and main. most important or largest: 2. MAIN definition: 1. wschzl ekdho ogcg xij gxsvaem mlwi mamg ddlt nrlfags nkjpq